Unlocks after you complete the first episode of Doodle God. You can unlock the puzzle with 50 mana.
Create a Flower using the limited elements you have available. If you are stuck trying to create the floor, you can use this walkthrough to help you complete the puzzle:
Fire + Water = Alcohol (Twice)
Fire + Alcohol = Energy (Twice)
Energy + Human = Wizard
Energy + Wizard = Demigod
Demigod + Nuclear Bomb = Flower